Oñate Celdrán Julián, Sanchez Rodríguez Carlos, Tomás Ros Mariano, González Valverde Francisco Miguel, Morga Egea Juan Pedro, Ruiz Marín Miguel, Valdelvira Nadal Pedro, Jiménez López José Miguel, Fontana Compiano Luis Oscar
Urology Department, Reina Sofia University Hospital, Murcia, Spain.
Arch Esp Urol. 2012 Jun;65(5):575-8.
To report a rare case of penile paraffinoma caused by the subcutaneous or intra-urethral injection of foreign substances containing long-chain saturated hydrocarbons. These were injected in order to increase the penis size which generated a chronic granulomatous inflammatory reaction. This is a rare practice in the western world.
We present the case of a 32-year-old Bulgarian male who presented with a two-year history of elastic, slightly painful penis swelling after subcutaneous liquid paraffin injection. The proposed treatment was excision of the affected tissue and penile reconstruction in a two-stage procedure.
The operative procedure was successful and the patient had good aesthetic and functional results. Paraffin and other materials injected into the penis can produce many complications. Foreign body granuloma, skin necrosis, penile deformity, chronic and unhealed ulcer, painful erection, and the inability to achieve a satisfactory sexual relationship are some of the resulting complications. Intralesional or systemic steroids have been used in primary sclerosing lipogranuloma resulting in the disappearance of the granuloma, but in our opinion the treatment of choice should be radical excision, and, if necessary, secondary reconstruction of the penis.
The injection of foreign substances to enhance penis size is currently an unjustifiable practice. However, it is still carried out, especially in Eastern Europe and Asia. In most cases surgical treatment is needed to treat the complications and the best modality seems to be radical excision together with follow-up.
报告一例罕见的阴茎石蜡瘤病例，该病例由皮下或尿道内注射含长链饱和烃的异物引起。注射这些物质是为了增大阴茎尺寸，从而引发慢性肉芽肿性炎症反应。这在西方世界是一种罕见的行为。
我们报告一例32岁的保加利亚男性病例，该患者在皮下注射液体石蜡后，阴茎出现弹性、轻度疼痛性肿胀已有两年病史。建议的治疗方法是分两阶段切除受影响组织并进行阴茎重建。
手术过程成功，患者获得了良好的美学和功能效果。注入阴茎的石蜡和其他物质可产生许多并发症。异物肉芽肿、皮肤坏死、阴茎畸形、慢性不愈合溃疡、疼痛性勃起以及无法实现满意的性关系等都是由此产生的并发症。局部或全身使用类固醇治疗原发性硬化性脂肪肉芽肿可使肉芽肿消失，但我们认为首选的治疗方法应是根治性切除，必要时进行阴茎二期重建。
注射异物以增大阴茎尺寸目前是一种不合理的行为。然而，这种行为仍在发生，尤其是在东欧和亚洲。在大多数情况下，需要手术治疗并发症，最佳方式似乎是根治性切除并进行随访。
