Master's degree program in Oral Surgery and Implantology, School of Dentistry of University of Barcelona, Spain.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Jul;114(1):43-8. doi: 10.1016/j.tripleo.2011.06.022. Epub 2012 Jan 2.
The objectives of this study were to identify the bacteria involved in delayed-onset infections after lower third molar removal and to determine the most suitable antibiotic for such complication.
Bacterial samples were collected from 13 patients who developed delayed-onset infections after lower third molar extraction. After the identification of the bacterial isolates, the in vitro antimicrobial susceptibility of the isolated strains was determined.
A total of 11 patients (12 samples) were finally included in the study. Up to 7 bacteria genera were identified. Fusobacterium sp. was present in 11 patients, Prevotella sp. in 8 cases, and Peptostreptococcus sp. in 7. Some strains of these bacteria were not susceptible to amoxicillin, amoxicillin/clavulanate, and metronidazol, whereas no resistances were found to clindamycin.
Fusobacterium sp., Prevotella sp., and Peptostreptococcus sp. are frequently present in delayed-onset infections after lower third molar removal. Based on the results of the microbial susceptibility tests, clindamycin seems to be the most adequate antibiotic for the treatment of this complication.
本研究旨在确定下颌第三磨牙拔除后迟发性感染涉及的细菌，并确定治疗这种并发症的最合适的抗生素。
从 13 名下颌第三磨牙拔除后发生迟发性感染的患者中采集细菌样本。在鉴定出细菌分离株后，测定分离株的体外抗菌药敏性。
最终共有 11 名患者（12 个样本）纳入研究。共鉴定出 7 种细菌属。11 例患者中均存在梭杆菌属，8 例患者中存在普雷沃菌属，7 例患者中存在消化链球菌属。这些细菌的一些菌株对阿莫西林、阿莫西林/克拉维酸和甲硝唑不敏感，而克林霉素则无耐药性。
梭杆菌属、普雷沃菌属和消化链球菌属在下颌第三磨牙拔除后迟发性感染中常被发现。基于微生物药敏试验结果，克林霉素似乎是治疗这种并发症的最合适的抗生素。
