Pinelli P, Pisano F, Miscio G
Department of Neurology, University of Milan, Italy.
J Neurol. 1990 Nov;237(7):405-9. doi: 10.1007/BF00314730.
In a long-standing case of myxoedema with ataxia and dysarthria, neurophysiological investigations were carried out to assess how much of the ataxic dysbasic syndrome depended on the slowness of mechanical contraction and how much resulted from primary cerebellar involvement. It was observed that the Achilles reflexogram showed a marked prolongation of contraction and relaxation time and that in both quadriceps and triceps surae mechanical percussion induced a marked myxoedema and prolonged relaxation time. The EMG of these muscles during voluntary contraction and stopping reaction detected an excessive recruitment of the antagonistic muscles, starting without any abnormal delay, a finding at variance with a typical cerebellar pattern. Post-urographic analysis gave a pattern of oscillations still within the normal range. These findings suggest that the gait alterations of our patient depended on the increase in muscle contraction time and the consequent excessive recruitment of the antagonists.
在一例患有共济失调和构音障碍的长期黏液性水肿病例中，进行了神经生理学检查，以评估共济失调性运动障碍综合征在多大程度上取决于机械收缩的缓慢程度，以及在多大程度上是由原发性小脑受累所致。观察到跟腱反射图显示收缩和舒张时间明显延长，并且在股四头肌和腓肠三头肌中，机械叩击均引起明显的黏液性水肿和舒张时间延长。在自愿收缩和停止反应期间，这些肌肉的肌电图检测到拮抗肌过度募集，且无任何异常延迟就开始，这一发现与典型的小脑模式不同。尿路造影后分析得出的振荡模式仍在正常范围内。这些发现表明，我们患者的步态改变取决于肌肉收缩时间的增加以及随之而来的拮抗肌过度募集。
