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[乳腺癌与肥胖,一种危险的关系]

[Breast cancer and obesity, a dangerous relation].

作者信息

Zaman Khalil, Bodmer Alexandre, Pralong François, Castiglione-Gertsch Monica

机构信息

Centre pluridisciplinaire d'oncologie, CHUV, 1011 Lausanne.

出版信息

Rev Med Suisse. 2012 May 23;8(342):1101-4.

Abstract

Obesity is associated with different cancers including breast cancer, whose incidence is increased in postmenopausal women. It has an adverse impact on the prognosis of the patients, regardless of their menopausal status. The fact of receiving a systemic adjuvant therapy does not neutralize the prognostic role of obesity. Moderate weight loss after cancer diagnosis could improve the outcome of the patients, while a weight gain during treatment seems without significant effect. Currently available data are still too incomplete to justify systematic programs to lose weight with an oncologic therapeutic aim. However, it is worth to encourage and support our patients to have an optimal diet, physical activity, and to lose weight as promotion of general health.

摘要

肥胖与包括乳腺癌在内的多种癌症相关,绝经后女性乳腺癌的发病率会升高。肥胖对患者的预后有不利影响,无论其绝经状态如何。接受全身辅助治疗这一事实并不能抵消肥胖的预后作用。癌症诊断后适度减重可改善患者的预后,而治疗期间体重增加似乎没有显著影响。目前可得的数据仍不完整,不足以证明以肿瘤治疗为目的的系统性减肥计划是合理的。然而,值得鼓励和支持我们的患者保持最佳饮食、进行体育锻炼并减重,以促进整体健康。

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