水溶性药物固态水解动力学参数的非线性估计。II：临界水分含量以下的合理呈现模式。

Nonlinear estimation of kinetic parameters for solid-state hydrolysis of water-soluble drugs. II: Rational presentation mode below the critical moisture content.

作者信息

Yoshioka S, Carstensen J T

机构信息

National Institute of Hygienic Sciences, Tokyo, Japan.

出版信息

J Pharm Sci. 1990 Sep;79(9):799-801. doi: 10.1002/jps.2600790911.

DOI:10.1002/jps.2600790911

PMID:2273463

Abstract

A logical presentation mode for accelerated data obtained at low relative humidities has been developed. A model is proposed leading to an equation relating the percent decomposition, x, at time t, to the temperature (T, K), and the water vapor (P, mmHg) in an open system. The data presented support the equation.

摘要

已经开发出一种用于呈现低相对湿度下获得的加速数据的逻辑模式。提出了一个模型，由此得出一个在开放系统中将时间t时的分解百分比x与温度（T，开尔文）和水蒸气（P，毫米汞柱）相关联的方程。所呈现的数据支持该方程。