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[大鼠子宫中³H-雌二醇、³H-组胺和³H-环磷酸腺苷定位的放射自显影研究]

[Radioautographic study of the localization of 3H-estradiol, 3H-histamine, and 3H-cyclic adenosine monophosphate in rat uterus].

作者信息

Deribas V I, Pankova T G

出版信息

Arkh Anat Gistol Embriol. 1979 Sep;77(9):92-7.

PMID:227347
Abstract

The method of radioautography has demonstrated that 3H-estradiol adheres to the nuclei of some myometrium cells, 3H-histamine is accepted by the cytoplasm of the majority of the myometrium cells, 3H-cyclic-AMP is selectively bound by the endothelial cells of capillaries and small vessels in all layers of the uterus. From the data obtained it is possible to conclude that estradiol and its mediators, histamine and cyclic-AMP, specifically interact with different cells and with different cell structures.

摘要

放射自显影法已证明,³H-雌二醇附着于一些子宫肌层细胞的细胞核,³H-组胺被大多数子宫肌层细胞的细胞质所摄取,³H-环磷酸腺苷被子宫各层毛细血管和小血管的内皮细胞选择性结合。从所获得的数据可以得出结论,雌二醇及其介质组胺和环磷酸腺苷与不同的细胞和不同的细胞结构发生特异性相互作用。

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Biochemical cascade mediating the estradiol action.介导雌二醇作用的生化级联反应。
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