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光声计算层析成像中的异质和衰减校正。

Photoacoustic computed tomography correcting for heterogeneity and attenuation.

机构信息

Washington University in St. Louis, Department of Biomedical Engineering, St. Louis, Missouri 63130, USA.

出版信息

J Biomed Opt. 2012 Jun;17(6):061211. doi: 10.1117/1.JBO.17.6.061211.

Abstract

We report an investigation of image reconstruction in photoacoustic tomography for objects that possess heterogeneous material and acoustic attenuation distributions. When the object contains materials, such as bone and soft-tissue, that are modeled using power law attenuation models with distinct exponents, we demonstrate that the effects of acoustic attenuation due to the most strongly attenuating material can be compensated for if the attenuation of the other less attenuating material(s) are neglected. Experiments with phantom objects are presented to validated our findings.

摘要

我们报告了一项针对具有不均匀材料和声衰减分布的物体的光声断层扫描图像重建的研究。当物体包含如骨和软组织等用具有不同指数的幂律衰减模型建模的材料时,如果忽略其他较弱衰减材料的衰减,则可以补偿由于最强烈衰减材料引起的声衰减的影响。通过对幻影物体的实验,验证了我们的发现。

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