胃食管反流病（GERD）患儿烦躁症状的非手术治疗综述。
A review of nonsurgical treatment for the symptom of irritability in infants with GERD.
作者信息
Neu Madalynn, Corwin Elizabeth, Lareau Suzanne C, Marcheggiani-Howard Cassandra
机构信息
University of Colorado College of Nursing, Aurora, Colorado, USA.
出版信息
J Spec Pediatr Nurs. 2012 Jul;17(3):177-92. doi: 10.1111/j.1744-6155.2011.00310.x. Epub 2011 Nov 1.
Abstract
PURPOSE
The purpose of this review was to assess effectiveness of nonsurgical treatment on irritable behavior of infants with gastroesophageal reflux disease.
DESIGN AND METHODS
A systematic literature review was conducted.
RESULTS
Research targeted treatment for irritability in infants with gastroesophageal reflux disease. All interventions including placebo were similar in reducing irritability. Which specific intervention is best for which infant is not yet known. Minor adverse effects that could increase discomfort in infants were found with pharmacologic treatments.
PRACTICE IMPLICATIONS
Knowledge of the effects of treatment on irritability and regurgitation can assist the nurse to work with other care providers in deciding how best to treat an individual infant.
摘要
目的
本综述的目的是评估非手术治疗对胃食管反流病婴儿易激行为的有效性。
设计与方法
进行了一项系统的文献综述。
结果
研究针对胃食管反流病婴儿的易激性进行治疗。所有干预措施（包括安慰剂）在减轻易激性方面相似。哪种具体干预措施对哪个婴儿最有效尚不清楚。药物治疗发现了可能增加婴儿不适的轻微不良反应。
实践意义
了解治疗对易激性和反流的影响可以帮助护士与其他护理人员共同决定如何最好地治疗个体婴儿。
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本文引用的文献
1
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomized trials.《CONSORT 2010声明：报告平行组随机试验的更新指南》
Open Med. 2010;4(1):e60-8. Epub 2010 Mar 24.
2
Symptoms and reflux in infants: Infant Gastroesophageal Reflux Questionnaire Revised (I-GERQ-R)--utility for symptom tracking and diagnosis.婴儿的症状与反流：婴儿胃食管反流问卷修订版（I-GERQ-R）——症状追踪与诊断的效用
Curr Gastroenterol Rep. 2010 Dec;12(6):431-6. doi: 10.1007/s11894-010-0140-1.
3
Efficacy and safety of pantoprazole delayed-release granules for oral suspension in a placebo-controlled treatment-withdrawal study in infants 1-11 months old with symptomatic GERD.在一项安慰剂对照的停药研究中，评估 1-11 个月大的有症状 GERD 婴儿使用泮托拉唑延迟释放颗粒口服混悬剂的疗效和安全性。
J Pediatr Gastroenterol Nutr. 2010 Jun;50(6):609-18. doi: 10.1097/MPG.0b013e3181c2bf41.
4
Effectiveness and safety of proton pump inhibitors in infantile gastroesophageal reflux disease.质子泵抑制剂治疗婴儿胃食管反流病的有效性和安全性。
Ann Pharmacother. 2010 Mar;44(3):572-6. doi: 10.1345/aph.1M519. Epub 2010 Feb 2.
5
Current pharmacological management of gastro-esophageal reflux in children: an evidence-based systematic review.儿童胃食管反流的当前药物治疗：一项基于证据的系统评价。
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6
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7
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8
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