与摄入L-色氨酸相关的嗜酸性粒细胞增多性肌痛综合征。

Eosinophilia-myalgia syndrome in association with L-tryptophan ingestion.

作者信息

Gresh J P, Vasey F B, Espinoza L R, Adelman H M, Germain B F

机构信息

University of South Florida College of Medicine, Department of Internal Medicine, Tampa.

出版信息

J Rheumatol. 1990 Nov;17(11):1557-8.

PMID:2273503

Abstract

The association between the recently described eosinophilia-myalgia syndrome and L-tryptophan is now well established. We describe a patient with eosinophilia-myalgia syndrome who developed incapacitating myalgias and peripheral eosinophilia responsive only to high dose corticosteroids. When massive upper gastrointestinal hemorrhage developed while receiving corticosteroid therapy, surgery was complicated by striking abdominal wall rigidness. A discussion of this case and of eosinophilia-myalgia syndrome is presented.

摘要

最近描述的嗜酸性粒细胞增多性肌痛综合征与L-色氨酸之间的关联现已明确确立。我们描述了一名患有嗜酸性粒细胞增多性肌痛综合征的患者，该患者出现了严重的肌痛和外周嗜酸性粒细胞增多，仅对高剂量皮质类固醇有反应。在接受皮质类固醇治疗期间发生大量上消化道出血时，手术因腹壁显著僵硬而变得复杂。本文对该病例及嗜酸性粒细胞增多性肌痛综合征进行了讨论。