[特应性皮炎（AD）患者使用螨虫成分进行斑贴试验的结果。第一篇报告。使用碾碎螨虫进行“原样斑贴试验”]

[Results of patch test using mite components in atopic dermatitis (AD) patients. 1st report. "As is patch test" using crushed mites].

作者信息

Kumei A, Nakayama H, Sakurai M, Tsurumachi K, Takaoka M

机构信息

Department of Deramtology, Saiseikai Central Hospital.

出版信息

Nihon Hifuka Gakkai Zasshi. 1990 Oct;100(11):1127-34.

PMID:2273575

Abstract

UNLABELLED

As is patch test using crushed live mites and crushed dried dead mites of Dermatophagoides pteronyssinus (D.p.), Dermatophagoides farinae (D.f.), & Tryophagus ptrescentiae (T.p.) was performed on 49 AD patients and 18 control patients suffering from dermatitis other than AD.

RESULTS

with crushed dried dead mites all patients showed negative reactions but with live mites 11 among 49 AD patients were positive (22.4%); 2) female mites were more positive than males at the rate 8:1; 3) with cases positive to mites, (a) D.p. was positive in all 11 positive cases (100%), (b) D.f. was negative in 5 cases (0%), and (c) T.p. was positive in 2 cases among 4 (50%); 4) because of the pathological manifestations of spongiosis and the infiltration of histiocytes and lymphocytes, the possibility of contact allergy to mite elements was suggested, as a mechanism of atopic dermatitis.

摘要

未标注

对49例特应性皮炎（AD）患者和18例患有除AD以外的其他皮炎的对照患者进行了斑贴试验，使用的是粉尘螨（D.p.）、屋尘螨（D.f.）和椭圆食粉螨（T.p.）的碾碎活螨和碾碎干死螨。

结果

1）使用碾碎干死螨时，所有患者均呈阴性反应，但使用活螨时，49例AD患者中有11例呈阳性（22.4%）；2）女性螨阳性率高于男性，比例为8:1；3）在螨阳性的病例中，（a）11例阳性病例中所有病例粉尘螨均呈阳性（100%），（b）5例屋尘螨呈阴性（0%），（c）4例中有2例椭圆食粉螨呈阳性（50%）；4）由于出现海绵形成以及组织细胞和淋巴细胞浸润的病理表现，提示对螨成分发生接触性过敏的可能性，作为特应性皮炎的一种机制。