Gottlieb James L, McDonnell William M, Day Ronald W, Yetman Anji T
Department of Pediatrics, Division of Pediatric Cardiology, University of Utah, Salt Lake City, UT, 84113, USA.
Pediatr Cardiol. 2012 Dec;33(8):1411-4. doi: 10.1007/s00246-012-0369-6. Epub 2012 Jun 27.
The change in clinical status of patients status post-Fontan surgery who relocated from low (<1,500 feet) to moderate (>4,000 feet) altitude was assessed. Cardiology databases were queried for patients meeting inclusion criteria. The clinical records of these patients for the 6 months before and 6 months after relocation were then reviewed. Between 1990 and 2010, 16 patients relocated to moderate altitude. All patients developed a new cardiac-related adverse event within 6 months of relocation. A decrease in New York Heart Association functional classification occurred in 15 (94 %) patients, and 11 (69 %) of these required hospitalization. Clinical deterioration at higher altitude is common in patients who have undergone Fontan surgery. Physicians at lower altitudes should caution these patients about the potential risks of relocation to moderate altitude.
对接受Fontan手术的患者从低海拔（<1500英尺）迁至中等海拔（>4000英尺）后临床状况的变化进行了评估。查询心脏病学数据库以获取符合纳入标准的患者。然后回顾了这些患者在搬迁前6个月和搬迁后6个月的临床记录。在1990年至2010年期间，16名患者迁至中等海拔地区。所有患者在搬迁后6个月内均出现了新的心脏相关不良事件。15名（94%）患者的纽约心脏协会功能分级下降，其中11名（69%）需要住院治疗。接受Fontan手术的患者在高海拔地区临床病情恶化很常见。低海拔地区的医生应告诫这些患者迁往中等海拔地区的潜在风险。
