Nakano T, Maeda J, Iwahashi N, Tamura S, Hada T, Higashino K
Third Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Jpn J Med. 1990 May-Jun;29(3):255-60. doi: 10.2169/internalmedicine1962.29.255.
The findings of Gallium-67 scans in eleven patients with malignant pleural mesothelioma were reviewed and compared to those of chest CT findings. All patients had an abnormal thoracic Ga-67 accumulation. Six out of 11 showed a diffuse accumulation over the entire involved hemithorax and a localized uptake was shown in 5. A marked diffuse thickening of pleura in the absence of adequate gallium accumulation was observed in one patient. Two out of 11 had a reduction of gallium uptake after having combination chemotherapy. These results suggest that a diffusely increased uptake over the entire involved hemithorax is the most characteristic finding of Ga-67 scan in malignant pleural mesothelioma, and that Ga-67 scans may be helpful as a valuable indicator of the proper therapy. However, the superiority of Ga-67 scan to thoracic CT as a means of determining the extent of disease process could not be verified.
回顾了11例恶性胸膜间皮瘤患者的镓-67扫描结果，并与胸部CT结果进行了比较。所有患者均有异常的胸部镓-67积聚。11例中有6例显示整个受累半侧胸腔弥漫性积聚，5例显示局部摄取。1例患者在没有足够镓积聚的情况下观察到胸膜明显弥漫性增厚。11例中有2例在联合化疗后镓摄取减少。这些结果表明，整个受累半侧胸腔弥漫性摄取增加是恶性胸膜间皮瘤镓-67扫描最具特征性的表现，镓-67扫描作为确定疾病进程范围的有价值指标可能会有所帮助。然而，镓-67扫描相对于胸部CT在确定疾病进程范围方面的优越性尚未得到证实。
