Rheumatology Department, Hospital do Servidor Público Estadual de São Paulo, Brazil.
Lupus. 2012 Oct;21(12):1356-8. doi: 10.1177/0961203312451203. Epub 2012 Jun 26.
Increased susceptibility to infection has long been observed among patients with systemic lupus erythematosus, and still represents a chief cause of morbidity and mortality in these patients. This is due in part to the severity of infection and to the difficulty of early diagnosis owing to the similarity between SLE flares and infection. Epidural infection is an uncommon condition, and a most rare condition caused by salmonella, which accounts for a broad spectrum of human illnesses from gastroenteritis and typhoid fever to the asymptomatic carrier state. We report the first case of epidural abscess caused by Salmonella enteritidis in a female with SLE with protean manifestations treated by intravenous antibiotics and surgery with full recovery of neurological symptoms, illustrating the importance of performing an early diagnosis and prompt treatment.
红斑狼疮患者易感染由来已久，目前仍是导致此类患者发病率和死亡率居高不下的主要原因。这部分是由于感染的严重性，以及由于狼疮发作和感染之间的相似性导致早期诊断困难。硬膜外感染较为少见，而由沙门氏菌引起的硬膜外脓肿则更为罕见，可引起从肠胃炎和伤寒到无症状带菌状态等广泛的人类疾病。我们报告了首例红斑狼疮女性表现多形性患者的沙门氏菌性硬膜外脓肿，该患者经静脉抗生素和手术治疗后完全恢复了神经症状，这说明了早期诊断和及时治疗的重要性。
