Ichigo Satoshi, Takagi Hiroshi, Matsunami Kazutoshi, Murase Takayuki, Ikeda Tsuneko, Imai Atsushi
Department of Obstetrics and Gynecology, Matsunami General Hospital, Gifu 501-6062, Japan.
Oncol Lett. 2012 Jan;3(1):3-6. doi: 10.3892/ol.2011.453. Epub 2011 Oct 21.
Transitional cell carcinoma (TCC) of the ovary is a rare recently recognized subtype of ovarian epithelial cancer. Ovarian TCC has a modest response to chemotherapy, and metastatic TCC from the renal pelvis results in mortality. The clinical presentation is indistinguishable from other types of ovarian carcinoma. Histopathological examination remains the first tool used in the diagnosis of these heterogeneous tumors and in the separation of closely related tumors. Since it is generally accepted that surgical resection is the primary therapeutic approach, and patient outcomes following chemotherapy are better than for other types of ovarian cancers, it is a reasonable concept to detect tumors when they are still confined within the ovaries. Thus, the aim of this review was to describe typical cases of primary TCC, and to review the medical literature for information on TCC management in order to determine appropriate diagnostic methods and therapy.
卵巢移行细胞癌(TCC)是一种最近才被认识到的罕见的卵巢上皮癌亚型。卵巢TCC对化疗反应一般,而来自肾盂的转移性TCC会导致死亡。其临床表现与其他类型的卵巢癌难以区分。组织病理学检查仍然是诊断这些异质性肿瘤以及区分密切相关肿瘤的首要工具。由于普遍认为手术切除是主要的治疗方法,且化疗后的患者预后比其他类型的卵巢癌更好,所以在肿瘤仍局限于卵巢内时进行检测是一个合理的概念。因此,本综述的目的是描述原发性TCC的典型病例,并查阅医学文献以获取有关TCC管理的信息,从而确定合适的诊断方法和治疗方案。