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膀胱同步性尿路上皮癌与脐尿管腺瘤并随后发生恶性转化。

Synchronous urothelial carcinoma of the bladder and urachal adenoma with subsequent malignant transformation.

作者信息

Pan David, Tay Yeng Kwang, Donnellan Scott

机构信息

Department of Urology, Monash Medical Centre, Southern Health, Victoria, Australia.

出版信息

Korean J Urol. 2012 Jun;53(6):438-40. doi: 10.4111/kju.2012.53.6.438. Epub 2012 Jun 19.

DOI:10.4111/kju.2012.53.6.438
PMID:22741056
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3382697/
Abstract

Malignant transformation of urachal adenoma is exceedingly rare, with intestinal metaplasia as the most common contributing mechanism. It is recommended that a urachal adenoma be regarded as a pre-malignant condition and be subject to endoscopic surveillance. A local en block excision of the tumor mass with urachalectomy and umbilectomy results in possible long-term survival. The median survival after platinum-based chemotherapy is limited for patients with extravesical disease. Here we report a case of synchronous urothelial carcinoma of the bladder and urachal adenoma that transformed into adenocarcinoma.

摘要

脐尿管腺瘤的恶性转化极为罕见，肠化生是最常见的促成机制。建议将脐尿管腺瘤视为癌前病变并进行内镜监测。对肿瘤肿块进行局部整块切除并切除脐尿管和脐部可实现长期生存。对于膀胱外疾病患者，铂类化疗后的中位生存期有限。在此，我们报告一例膀胱尿路上皮癌与脐尿管腺瘤同时发生且后者转化为腺癌的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/d402405825c4/kju-53-438-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/78037faeef49/kju-53-438-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/edc403470e06/kju-53-438-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/d402405825c4/kju-53-438-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/78037faeef49/kju-53-438-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/edc403470e06/kju-53-438-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/596a/3382697/d402405825c4/kju-53-438-g003.jpg

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