Liu Long-Fei, Wang Long, Lu Te-Fei, Qi Lin, Zu Xiong-Bing
Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Zhonghua Nan Ke Xue. 2012 May;18(5):441-5.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition obsessing urologists and patients. It is also known as a heterogeneous syndrome, with varied etiologies, progression courses and responses to treatment. Based on the deeper insights into its pathogenesis and re-evaluation of its clinical trials, a novel phenotypic classification system UPOINT has been developed, which clinically classifies CP/CPPS patients into six domains: urinary (U), psychosocial (P), organ-specific (O), infection (I) , neurologic/systemic (N) and tenderness of pelvic floor skeletal muscles (T), and directs individualized and multimodal therapeutic approaches to CP/CPPS. This review systematically summarizes the theoretical foundation, clinical characteristics of UPOINT and treatment strategies based on the UPOINT phenotypic classification system.
慢性前列腺炎/慢性盆腔疼痛综合征（CP/CPPS）是困扰泌尿外科医生和患者的常见病症。它也被认为是一种异质性综合征，病因、病程及对治疗的反应各不相同。基于对其发病机制的深入认识及对临床试验的重新评估，一种新的表型分类系统UPOINT被开发出来，该系统将CP/CPPS患者在临床上分为六个领域：排尿（U）、心理社会（P）、器官特异性（O）、感染（I）、神经/系统性（N）和盆底骨骼肌压痛（T），并指导针对CP/CPPS的个体化和多模式治疗方法。本综述系统总结了UPOINT的理论基础、临床特征以及基于UPOINT表型分类系统的治疗策略。
