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硅酮栓引起的泪小管反应性淋巴增生。

Reactive lymphoid hyperplasia of lacrimal canaliculus caused by a silicone plug.

机构信息

Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

出版信息

Ophthalmic Plast Reconstr Surg. 2012 Nov-Dec;28(6):e138-40. doi: 10.1097/IOP.0b013e318249d406.

Abstract

Complications of tumorigenesis by a lacrimal silicone plug are rarely reported and most of them were cases of granuloma due to chronic inflammation. The authors present a case of a 57-year-old healthy woman complaining of lower eyelid swelling and protruding mass from lower punctum who had undergone insertion of a lacrimal silicone plug. Surgical mass resection was performed and initial histopathology revealed lymphoid hyperplasia. Additional immunophenotypic markers CD3, CD20, and BCL2 showed reactive lymphoid hyperplasia. It has a histopathologic significance in that it can mimic lymphoma and should be distinguished from malignancy.

摘要

泪道硅酮塞致肿瘤并发症罕见报道,多为慢性炎症导致的肉芽肿。作者报告了 1 例 57 岁健康女性,因下眼睑肿胀和下泪小点突出肿块就诊,该患者曾行泪道硅酮塞植入术。行肿块切除术,最初的组织病理学显示淋巴组织增生。进一步的免疫表型标志物 CD3、CD20 和 BCL2 显示反应性淋巴组织增生。其具有组织病理学意义,因为它可以模拟淋巴瘤,应与恶性肿瘤相鉴别。

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