Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ophthalmic Plast Reconstr Surg. 2012 Nov-Dec;28(6):e138-40. doi: 10.1097/IOP.0b013e318249d406.
Complications of tumorigenesis by a lacrimal silicone plug are rarely reported and most of them were cases of granuloma due to chronic inflammation. The authors present a case of a 57-year-old healthy woman complaining of lower eyelid swelling and protruding mass from lower punctum who had undergone insertion of a lacrimal silicone plug. Surgical mass resection was performed and initial histopathology revealed lymphoid hyperplasia. Additional immunophenotypic markers CD3, CD20, and BCL2 showed reactive lymphoid hyperplasia. It has a histopathologic significance in that it can mimic lymphoma and should be distinguished from malignancy.
泪道硅酮塞致肿瘤并发症罕见报道,多为慢性炎症导致的肉芽肿。作者报告了 1 例 57 岁健康女性,因下眼睑肿胀和下泪小点突出肿块就诊,该患者曾行泪道硅酮塞植入术。行肿块切除术,最初的组织病理学显示淋巴组织增生。进一步的免疫表型标志物 CD3、CD20 和 BCL2 显示反应性淋巴组织增生。其具有组织病理学意义,因为它可以模拟淋巴瘤,应与恶性肿瘤相鉴别。