[乳蛋白的交叉反应性：放射变应原吸附试验结果的统计分析]
[Cross-reactivity of milk proteins: statistical analysis of RAST results].
作者信息
Di Berardino L, Angrisano A, Zatta G, Fregoso A, Bagliani G, Compostella R
机构信息
Divisione di Pediatria, Presidio Ospedaliero di Bollate Milano, Italia.
出版信息
Pediatr Med Chir. 1990 May-Jun;12(3):237-8.
RIA dosages of specific IgE antibodies to cow milk, alpha-lactalbumin, beta-lactoglobulin, casein, cheddar and mould cheese were determined in 440 patients. Statistic analysis has been carried out with: 1) the linear regression and correlation coefficient r2: 2) U test of Mann-Whitney and then S test of Kendall Results show that casein has low allergenicity in comparison to other cow's milk proteins. It could be unnecessary to quantify specific IgE to cow milk and cheeses. From the observed data we could suppose that the formulas with casein/blood protein ratio similar to maternal milk may be more allergenic than casein based ones.
对440名患者测定了针对牛奶、α-乳白蛋白、β-乳球蛋白、酪蛋白、切达干酪和霉菌干酪的特异性IgE抗体的放射免疫分析剂量。进行了以下统计分析：1）线性回归和相关系数r2；2）曼-惠特尼U检验，然后是肯德尔S检验。结果表明，与其他牛奶蛋白相比，酪蛋白的致敏性较低。可能没有必要对牛奶和奶酪的特异性IgE进行定量。从观察到的数据可以推测，酪蛋白/血蛋白比率与母乳相似的配方奶粉可能比基于酪蛋白的配方奶粉更具致敏性。
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