Pifferí M, Michelotti F, Domenici R, Fiorini V, Michelotti F, Ceccarelli M
Istituto di Clinica Pediatrica, Università di Pisa, Italia.
Pediatr Med Chir. 1990 May-Jun;12(3):251-4.
The study of bile acids in the newborn permits to the AA. to point out that the beginning of the feeding does not influence the "physiologic cholestasis" of the first days of life. Neonatal cholestasis is the expression of the immaturity of bile acids synthesis and hepatic and intestinal carriage, which is not correlated with the maternal conditions. Furthermore, the AA. discuss about the analogy between cholestasis and "physiologic hyperbilirubinemia", from which it differs for the longer time. In fact, the maturation of the enterohepatic circle occurs very slowly under possible dietetic factors influences.
对新生儿胆汁酸的研究使作者能够指出,开始喂养并不影响生命最初几天的“生理性胆汁淤积”。新生儿胆汁淤积是胆汁酸合成以及肝脏和肠道转运不成熟的表现,与母亲的状况无关。此外,作者讨论了胆汁淤积与“生理性高胆红素血症”之间的相似性,两者的区别在于胆汁淤积持续时间更长。事实上,在可能的饮食因素影响下,肠肝循环的成熟非常缓慢。