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脊柱侧弯治疗中脊柱内固定椎弓根螺钉密度的生物力学分析:初步结果

Biomechanical analysis of pedicle screw density in spinal instrumentation for scoliosis treatment: first results.

作者信息

Wang Xiaoyu, Aubin Carl-Eric, Larson A Noelle, Labelle Hubert, Parent Stefan

机构信息

École Polytechnique de Montréal, Montréal, Canada.

出版信息

Stud Health Technol Inform. 2012;176:303-6.

PMID:22744515
Abstract

Clinical studies reveal remarkable variation in screw patterns, or screw density in spinal instrumentation. Screw density may have a great impact on blood loss, operative time, radiation, risk of screw malposition, and cost. Thus, there is a need to understanding of the biomechanical effects of screw density so as to minimize the number of pedicle screws while ensuring safe and effective instrumentation. The objective of this study was to compare the deformity correction effects and bone-screw loadings of different pedicle screw densities in spinal instrumentation for scoliosis treatment. Spinal instrumentation simulations were performed on three scoliosis patients using 3 screw density patterns (low, preferred, and high screw density) proposed by two experienced surgeons and basic correction techniques: concave rod attachment, rod derotation, apical vertebral derotation, and convex side rod attachment. Simulation results showed that all tested screw densities generated quite similar correction, with differences between the achieved corrections all below 3°. The average bone-screw forces were 244±67N, 214±66 N, and 210±71 N, respectively for low, preferred, and high densities. It remains a complex challenge balancing the benefit of load sharing between more implants with the overconstraints and limited degrees of freedom introduced by the increased number of implants. Studies on additional screw densities and patterns proposed by more surgeons for a variety of cases, and using more diverse correction techniques are necessary to draw stronger conclusions and to recommend the optimal screw density.

摘要

临床研究表明,脊柱内固定中螺钉模式或螺钉密度存在显著差异。螺钉密度可能对失血、手术时间、辐射、螺钉位置不当风险和成本产生重大影响。因此,有必要了解螺钉密度的生物力学效应,以便在确保安全有效的内固定的同时尽量减少椎弓根螺钉的数量。本研究的目的是比较脊柱侧弯治疗中不同椎弓根螺钉密度在脊柱内固定中的畸形矫正效果和骨-螺钉负荷。使用两位经验丰富的外科医生提出的三种螺钉密度模式(低、优选和高螺钉密度)和基本矫正技术(凹侧棒连接、棒旋转、顶椎旋转和凸侧棒连接)对三名脊柱侧弯患者进行了脊柱内固定模拟。模拟结果表明,所有测试的螺钉密度产生的矫正效果非常相似,所实现的矫正之间的差异均低于3°。低、优选和高密度的平均骨-螺钉力分别为244±67N、214±66N和210±71N。在更多植入物之间的负荷分担益处与增加植入物数量所带来的过度约束和有限自由度之间取得平衡仍然是一个复杂的挑战。有必要对更多外科医生针对各种病例提出的额外螺钉密度和模式进行研究,并使用更多样化的矫正技术,以得出更有力的结论并推荐最佳螺钉密度。

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