Ahn Jeong-Hwan, Kong Mihee
Department of Family Medicine, Jeju National University Hospital, Jeju, Korea.
Korean J Fam Med. 2011 Nov;32(7):406-11. doi: 10.4082/kjfm.2011.32.7.406. Epub 2011 Nov 30.
Pulse wave velocity (PWV) and ankle-brachial pressure index (ABI) are non-invasive tools to measure atherosclerosis and arterial stiffness. Heart rate variability (HRV) has proven to be a non-invasive powerful tool in the investigation of the autonomic cardiovascular control. Therefore, the purpose of this study was to determine the relationship among PWV, ABI, and HRV parameters in adult males.
The study was carried out with 117 males who visited a health care center from April, 2009 to May, 2010. We conducted blood sampling (total cholesterol, triglyceride, high density lipoprotein, cholesterol, fasting glucose) and physical examination. We studied brachial-ankle PWV (baPWV) and ABI. We examined HRV parameters including standard deviation of NN interval (SDNN), low frequency (LF), high frequency (HF), LF/HF ratio. We analyzed the relationship among baPWV, ABI, and HRV parameters.
SDNN had a significant negative correlation with age, systolic blood pressure and heart rate. LF and HF had a significant negative correlation with age, and age and heart rate, respectively. baPWV was significantly and positively associated with age, systolic and diastolic blood pressures, total cholesterol, fasting glucose and heart rate. ABI was negative correlated significantly with systolic and diastolic blood pressures and heart rate. After adjusting for all associated variables, baPWV was not correlated with HRV parameters, but there was a significant positive association between SDNN and ABI (r = 0.195, P = 0.014).
SDNN of HRV parameters had a significant positive correlation with ABI.
脉搏波速度(PWV)和踝臂血压指数(ABI)是用于测量动脉粥样硬化和动脉僵硬度的非侵入性工具。心率变异性(HRV)已被证明是研究自主心血管控制的一种强大的非侵入性工具。因此,本研究的目的是确定成年男性中PWV、ABI和HRV参数之间的关系。
该研究对2009年4月至2010年5月期间到一家医疗保健中心就诊的117名男性进行。我们进行了血液采样(总胆固醇、甘油三酯、高密度脂蛋白、胆固醇、空腹血糖)和体格检查。我们研究了臂踝脉搏波速度(baPWV)和ABI。我们检测了HRV参数,包括NN间期标准差(SDNN)、低频(LF)、高频(HF)、LF/HF比值。我们分析了baPWV、ABI和HRV参数之间的关系。
SDNN与年龄、收缩压和心率呈显著负相关。LF和HF分别与年龄、年龄和心率呈显著负相关。baPWV与年龄、收缩压和舒张压、总胆固醇、空腹血糖和心率呈显著正相关。ABI与收缩压和舒张压以及心率呈显著负相关。在对所有相关变量进行校正后,baPWV与HRV参数无相关性,但SDNN与ABI之间存在显著正相关(r = 0.195,P = 0.014)。
HRV参数中的SDNN与ABI呈显著正相关。