Diving Diseases Research Centre, The Hyperbaric Medical Centre, Plymouth, Devon, UKDepartment of Wound Healing, Cardiff University, Cardiff, UK.
Int Wound J. 2014 Feb;11(1):28-34. doi: 10.1111/j.1742-481X.2012.01034.x. Epub 2012 Jul 2.
Hyperbaric oxygen therapy (HBO) has been used as an adjunct for healing diabetic foot ulcers (DFUs) for decades. However, its use remains controversial. A literature search was conducted to locate clinical studies and assess the available evidence. Ten prospective and seven retrospective studies evaluating HBO for DFUs were located. These were reviewed and the outcomes were discussed. One study reported no difference in outcomes between patients receiving hyperbaric oxygen and the control group. However, their regime differed from all other studies in that the patients received hyperbaric oxygen twice rather than once daily. Reduced amputation rates and improved healing were the most common outcomes observed.
高压氧治疗（HBO）作为治疗糖尿病足溃疡（DFUs）的辅助手段已经使用了几十年。然而，其应用仍然存在争议。进行了文献检索以查找临床研究并评估现有证据。共找到十项前瞻性研究和七项回顾性研究评估了 HBO 治疗 DFUs。对这些研究进行了回顾，并讨论了结果。一项研究报告称，接受高压氧治疗的患者与对照组的结果无差异。然而，他们的治疗方案与所有其他研究不同，因为患者每天接受两次高压氧治疗，而不是一次。最常见的观察结果是降低截肢率和改善愈合。
