Chan Calvin H Y, Telford Jennifer J
Division of Gastroenterology, St Paul's Hospital, The University of British Columbia, Vancouver, BC, Canada.
Gastrointest Endosc Clin N Am. 2012 Jul;22(3):511-37. doi: 10.1016/j.giec.2012.05.005.
Endoscopic retrograde cholangiopancreatography (ERCP) is the first-line management in most situations when a benign biliary stricture is suspected. Although management principles are similar in all subgroups, the anticipated response rates, need for ancillary medical and endoscopic approaches, and use of less proven strategies vary between differing causes. Exclusion of malignancy should always be a focus of management. Newer endoscopic techniques such as endoscopic ultrasound, cholangioscopy, confocal endomicroscopy, and metal biliary stenting are increasingly complementing traditional ERCP techniques in achieving long-term sustained stricture resolution. Surgery remains a definitive management alternative when a prolonged trial of endoscopic therapy does not achieve treatment goals.
当怀疑存在良性胆管狭窄时,在大多数情况下,内镜逆行胰胆管造影术(ERCP)是一线治疗方法。尽管所有亚组的治疗原则相似,但不同病因之间的预期缓解率、辅助医学和内镜方法的需求以及较少使用的策略的应用存在差异。排除恶性肿瘤始终应是治疗的重点。诸如内镜超声、胆管镜检查、共聚焦内镜显微镜检查和金属胆道支架置入术等更新的内镜技术,在实现长期持续性狭窄缓解方面,越来越多地补充了传统的ERCP技术。当长期的内镜治疗试验未达到治疗目标时,手术仍然是一种确定性的治疗选择。