Division of Cardiology, UCSF Medical Center, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0124, USA.
Heart Fail Clin. 2012 Jul;8(3):301-17. doi: 10.1016/j.hfc.2012.04.013.
Pulmonary hypertension (PH) can develop in association with many different diseases and risk factors, and its presence is nearly always associated with reduced survival. The prognosis and management of PH is largely dependent upon its underlying etiology and severity of disease. The combination of clinical and hemodynamic classifications of PH provides a framework for the diagnostic evaluation of PH to establish a final clinical diagnosis that guides therapy. As our understanding of the different pathologic mechanisms that underlie the syndrome of PH evolves, so too will the classification and treatment of PH.
肺动脉高压(PH)可由多种不同的疾病和危险因素引起,其存在几乎总是与生存率降低相关。PH 的预后和管理在很大程度上取决于其潜在病因和疾病严重程度。PH 的临床和血流动力学分类的结合为 PH 的诊断评估提供了一个框架,以确定最终的临床诊断,指导治疗。随着我们对 PH 综合征的不同病理机制的理解不断发展,PH 的分类和治疗也将随之发展。