Department of Thoracic and Cardiovascular Surgery, Gerald McGinnis Cardiovascular Institute, Allegheny General Hospital, 320 East North Avenue, Pittsburgh, PA 15212, USA.
Heart Fail Clin. 2012 Jul;8(3):475-83. doi: 10.1016/j.hfc.2012.04.003.
Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition characterized by obstruction of pulmonary arterial vasculature by acute or recurrent thromboemboli with subsequent organization, leading to progressive pulmonary hypertension and right heart failure. Until relatively recently, CTEPH was a diagnosis made primarily at autopsy, but advances made in diagnostic modalities and surgical pulmonary endarterectomy techniques have made this disease treatable and even potentially curable. Although published guidelines are available, in the absence of randomized controlled trials regarding CTEPH there is a lack of standardization, and treatment options have to be individualized.
慢性血栓栓塞性肺动脉高压（CTEPH）是一种潜在的危及生命的疾病，其特征是急性或复发性血栓栓塞导致肺血管阻塞，随后发生组织纤维化，导致进行性肺动脉高压和右心衰竭。直到最近，CTEPH 主要是在尸检时做出的诊断，但诊断方法和肺动脉内膜切除术技术的进步使这种疾病可以治疗，甚至可能治愈。尽管已经有了发表的指南，但由于缺乏关于 CTEPH 的随机对照试验，因此缺乏标准化，治疗方案必须个体化。
