Department of Obstetrics and Gynecology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA.
J Minim Invasive Gynecol. 2012 Jul-Aug;19(4):422-33. doi: 10.1016/j.jmig.2012.03.022.
Vasopressin has been used in gynecologic surgery since the 1950s. Since its initial introduction, multiple applications of vasopressin have been explored. The expansion of vasopressin usage in gynecologic surgery is being fueled in part by the increase in minimally invasive surgical techniques, in which alternative methods of temporary hemostasis are in high demand. Nevertheless, much criticism has been directed toward use of vasopressin because of reports of serious complications including cardiac arrest. These concerns have caused several countries to restrict or prohibit the use of this valuable drug. This review explores the mechanisms of vasopressin, the current literature on vasopressin use in gynecologic surgery, and evaluates the reported complications associated with vasopressin use.
加压素自 20 世纪 50 年代以来就被应用于妇科手术。自最初引入以来，已经探索了加压素的多种应用。加压素在妇科手术中的使用范围扩大，部分原因是微创技术的增加，这些技术对临时止血的替代方法的需求很高。然而，由于加压素的使用导致包括心脏骤停在内的严重并发症的报道，人们对此提出了很多批评。这些担忧导致一些国家限制或禁止使用这种有价值的药物。这篇综述探讨了加压素的作用机制，以及加压素在妇科手术中的应用的现有文献，并评估了与加压素使用相关的报告并发症。
