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[胸腺库尔洛夫小体。对大鼠卵子发生的作用]

[Thymic Kurloff inclusion. Action on the ovogenesis of the rat].

作者信息

de Graeve P, Guilhem A, Amiel S, Bimes C

出版信息

Bull Assoc Anat (Nancy). 1978 Dec;62(179):401-9.

PMID:227495
Abstract

Grafts and injections of cellular extracts from thymus and spleen of guinea pigs, were carried out in puberal and impuberal female rats. These organs are especially rich in Foa-Kurloff cells after oestrogentherapy. Kidney served as a reference material for the same experimental conditions. Controls received cellular injections and grafts from guinea pig organs without treatment. In all cases, ovarian histological and biometric study of recipient animals shows no alteration of the ovarian cycle. On the other hand, grafts and injections of cellular extracts from organs with high concentration of Foa-Kurloff cells induced hyperactivity of internal theca folliculi and of ovarian interstitial cells, only in puberal female rats.

摘要

对青春期和未青春期的雌性大鼠进行了豚鼠胸腺和脾脏细胞提取物的移植和注射。在雌激素治疗后,这些器官中富含福阿-库尔洛夫细胞。在相同实验条件下,肾脏用作参考材料。对照组接受未经处理的豚鼠器官的细胞注射和移植。在所有情况下,对受体动物的卵巢进行组织学和生物测量研究表明,卵巢周期没有改变。另一方面,仅在青春期雌性大鼠中,注射和移植来自福阿-库尔洛夫细胞浓度高的器官的细胞提取物会诱导卵泡内膜和卵巢间质细胞的过度活跃。

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