Belarusian State Medical University, Infectious Diseases Department, Hospital of Infectious Diseases, Kropotkina str., b.76, Minsk 220050, Belarus.
Vaccine. 2012 Aug 3;30(36):5324-6. doi: 10.1016/j.vaccine.2012.06.055. Epub 2012 Jun 28.
Here we report horizontal symptomatic transmission of the Leningrad-Zagreb (L-Zagreb) mumps vaccine virus. Children who were the source of transmission had been vaccinated with the MMR vaccine (Serum Institute of India) contained L-Zagreb mumps virus. This is the first report of horizontal symptomatic transmission of this vaccine. The etiology of all seven contact cases was confirmed by epidemiological linking, serology and by F, SH, NP and HN mumps virus genes sequencing.
我们在此报告了 Leningrad-Zagreb(L-Zagreb)腮腺炎疫苗病毒的水平传播。作为传染源的儿童曾接种过含有 L-Zagreb 腮腺炎病毒的麻疹、腮腺炎、风疹联合疫苗(印度血清研究所)。这是首例报告的这种疫苗的水平传播。所有七例接触病例的病因均通过流行病学关联、血清学以及 F、SH、NP 和 HN 腮腺炎病毒基因测序得到确认。