经导管去肾交感神经术治疗抵抗性高血压：谨慎乐观。

Renal denervation to treat resistant hypertension: Guarded optimism.

机构信息

Department of Nephrology and Hypertension, Glickman Urological and Kidney Institute, Cleveland Clinic.

出版信息

Cleve Clin J Med. 2012 Jul;79(7):501-10. doi: 10.3949/ccjm.79a.12040.

DOI:10.3949/ccjm.79a.12040

Abstract

Renal sympathetic denervation has shown promise in treating hypertension resistant to drug therapy. This procedure lowers blood pressure via targeted attenuation of renal sympathetic tone, and it has a favorable safety profile. But although there is reason for cautious optimism, we should keep in mind that the mechanisms of hypertension are complex and multifactorial, and further study of this novel therapy and its long-term effects is needed.

摘要

肾去交感神经术在治疗药物抵抗性高血压方面显示出良好的前景。该手术通过靶向减弱肾交感神经张力来降低血压，具有良好的安全性。但是，尽管有理由谨慎乐观，但我们应该记住，高血压的机制是复杂的和多因素的，需要进一步研究这种新疗法及其长期效果。