婴儿同时患有脉络丛癌和肾上腺皮质肿瘤。

Coincident choroid plexus carcinoma and adrenocortical tumor in an infant.

机构信息

Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, 23-3, Shimoaizuki, Eiheiji-cho, Fukui, 910-1193, Japan.

出版信息

Brain Tumor Pathol. 2013 Apr;30(2):104-8. doi: 10.1007/s10014-012-0112-2. Epub 2012 Jul 1.

DOI:10.1007/s10014-012-0112-2

PMID:22752623

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3627043/

Abstract

We report a case of a 20-month-old girl with a large choroid plexus carcinoma arising in the left lateral ventricle and an adrenocortical tumor. Following brain tumor resection, the patient was treated with radiation and chemotherapy. The adrenocortical tumor was found with the manifestation of precocious puberty. TP53 gene mutation (exons 4-10) was not detected in either specimen. The patient had leptomeningeal dissemination and died 26 months later.

摘要

我们报告了一例 20 个月大的女孩，其左侧侧脑室中出现了大型脉络丛癌和肾上腺皮质肿瘤。脑肿瘤切除后，患者接受了放疗和化疗。肾上腺皮质肿瘤表现为性早熟。两个标本均未检测到 TP53 基因突变（外显子 4-10）。患者出现了脑膜播散，26 个月后死亡。