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一名维生素C缺乏儿童出现双侧眼球突出。

Bilateral proptosis in a child with vitamin C deficiency.

作者信息

Saha Pritam, Pal Radha Binod, Das Ira, Sinha Malay Kumar

机构信息

Department of Pediatrics, Medical College & Hospital, 88, College Street, Kolkata 700073, West Bengal, India.

出版信息

Int Ophthalmol. 2012 Dec;32(6):599-601. doi: 10.1007/s10792-012-9602-9. Epub 2012 Jul 1.

DOI:10.1007/s10792-012-9602-9
PMID:22752649
Abstract

Scurvy is one of the oldest diseases known to mankind, caused by vitamin C deficiency. Nowadays it exists primarily in certain vulnerable populations such as patients with neurodevelopmental disabilities. Proptosis due to orbital haemorrhage is a rare complication of scurvy. Here we describe a case of diaplegic cerebral palsy presented with sudden onset of bilateral proptosis and swollen and tender knee joints. Subsequent computed tomography of the orbit revealed hematoma in the superior aspect of both orbits in the extraconal position. X-ray of the knee joints revealed bony changes consistent with scurvy. After 6 weeks of treatment with vitamin C orally, the proptosis and the bony changes returned to normal. Although scurvy is a rare disease in the general pediatric population, it still exists in certain vulnerable populations like neurologically disabled ones, and this uncommon cause for proptosis should be considered in such children.

摘要

坏血病是人类已知的最古老疾病之一,由维生素C缺乏引起。如今,它主要存在于某些弱势群体中,如神经发育障碍患者。眼眶出血导致的眼球突出是坏血病的一种罕见并发症。在此,我们描述一例双瘫型脑瘫患者,其突然出现双侧眼球突出以及膝关节肿胀和压痛。随后的眼眶计算机断层扫描显示双侧眶锥外上象限有血肿。膝关节X线检查显示与坏血病相符的骨质改变。口服维生素C治疗6周后,眼球突出和骨质改变恢复正常。尽管坏血病在普通儿科人群中是一种罕见疾病,但在某些弱势群体如神经功能残疾者中仍然存在,对于这类儿童应考虑这种不常见的眼球突出病因。

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引用本文的文献

1
Unusual case of 'scorbutic proptosis'.罕见的坏血病眼球突出病例。
BMJ Case Rep. 2024 Jan 31;17(1):e253380. doi: 10.1136/bcr-2022-253380.
2
When the limp has a dietary cause: A retrospective study on scurvy in a tertiary Italian pediatric hospital.当跛行由饮食原因引起时:意大利一家三级儿科医院坏血病的回顾性研究。
Front Pediatr. 2022 Sep 14;10:981908. doi: 10.3389/fped.2022.981908. eCollection 2022.
3
Bifrontal Epidural Hemorrhage Secondary to Scurvy in a 10-Year-Old Boy.一名10岁男孩因坏血病继发双侧额叶硬膜外出血

本文引用的文献

1
Hemorrhagic pleural effusion: can it be scurvy?血性胸腔积液:会是坏血病吗?
Indian J Pediatr. 2007 Nov;74(11):1050-1. doi: 10.1007/s12098-007-0198-4.
2
Scurvy and rickets masked by chronic neurologic illness: revisiting "psychologic malnutrition".慢性神经疾病掩盖下的坏血病和佝偻病:重新审视“心理性营养不良”
Pediatrics. 2007 Mar;119(3):e783-90. doi: 10.1542/peds.2006-1071.
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SIMULTANEOUS BILATERAL OCULAR HAEMORRHAGES IN SCURVY.坏血病并发双侧眼部出血
Clin Pediatr (Phila). 2022 Nov;61(11):745-748. doi: 10.1177/00099228221103975. Epub 2022 Aug 17.
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Scurvy in pediatric age group - A disease often forgotten?小儿年龄组中的坏血病——一种常被遗忘的疾病?
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[A case of scurvy with alveolar hemorrhage].[一例伴有牙槽出血的坏血病]
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Infantile scurvy: a historical perspective.婴儿坏血病:历史视角
Pediatrics. 2001 Oct;108(4):E76. doi: 10.1542/peds.108.4.e76.
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Scurvy--an unusual cause of proptosis?坏血病——眼球突出的罕见病因?
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Scurvy--the forgotten cause of proptosis.
Indian Pediatr. 1983 Dec;20(12):952-3.