采用酶免疫测定法快速诊断链球菌性咽炎。
Rapid diagnosis of streptococcal pharyngitis with enzyme immunoassay.
作者信息
Chu J M, Chen J M, Wu M H, Hong J Y, Wang Y M, Hsu H H, Lue H C
机构信息
Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
出版信息
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1990 May-Jun;31(3):151-7.
From June 1988 to May 1989, 444 throat swab specimens were tested with an enzyme immunoassay kit for rapid diagnosis of group A streptococcal pharyngitis. The results were compared with those of throat culture method. The rapid test was positive in 37 of 42 culture-positive specimens and negative in 379 of 402 culture-negative specimens, thus yielding a total agreement of 93.7%, sensitivity 88.1%, specificity 94.7%, positive predictive value 61.7%, negative predictive value 98.7%. According to this practical application, we suggest that enzyme immunoassay test can be applied in outpatient clinics by busy pediatricians for rapid diagnosis of group A streptococcal pharyngitis.
1988年6月至1989年5月，采用酶免疫分析试剂盒对444份咽拭子标本进行检测，以快速诊断A组链球菌性咽炎。将结果与咽培养法的结果进行比较。快速检测在42份培养阳性标本中有37份呈阳性，在402份培养阴性标本中有379份呈阴性，总符合率为93.7%，敏感性为88.1%，特异性为94.7%，阳性预测值为61.7%，阴性预测值为98.7%。根据这一实际应用情况，我们建议忙碌的儿科医生可在门诊使用酶免疫分析检测法快速诊断A组链球菌性咽炎。
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