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转移性凝血病性硬膜下血肿:预后不佳。

Metastatic coagulopathic subdural hematoma: A dismal prognosis.

作者信息

George Kuriakose J, Lau Anthony, Ellis Michael, Kiehl Tim-Rasmus, Fehlings Michael G

机构信息

Department of Neurosurgery, Toronto Western Hospital, Toronto, Ontario, Canada.

出版信息

Surg Neurol Int. 2012;3:60. doi: 10.4103/2152-7806.97004. Epub 2012 Jun 9.

Abstract

BACKGROUND

Dural metastases have been found in about 8-9% of patients who died of cancer, in most autopsy series. Dural metastases presenting with chronic subdural hematoma are rare, with only about 55 cases reported in the literature.

CASE DESCRIPTION

We discuss the case of a 72 year old gentleman with prostate cancer who presented with a chronic subdural hematoma which was drained surgically. He was found to have disseminated intravascular coagulation (DIC) and recurrence of the subdural hematoma for which further drainage was required. After the second drainage of the chronic subdural hematoma, dural metastases were diagnosed from the pathology specimens.

CONCLUSION

On reviewing the literature, 25 cases of dural metastases with chronic subdural hematoma and coagulopathy were found. These cases were characterized by the fact that they had a very poor clinical outcome in spite of surgical drainage. This combination could be a distinct entity and its recognition is important to guide management of this rare condition.

摘要

背景

在大多数尸检系列中,约8-9%死于癌症的患者发现有硬脑膜转移。表现为慢性硬膜下血肿的硬脑膜转移很少见,文献中仅报道了约55例。

病例描述

我们讨论了一例72岁前列腺癌男性患者,其表现为慢性硬膜下血肿并接受了手术引流。发现他患有弥散性血管内凝血(DIC)且硬膜下血肿复发,需要进一步引流。在慢性硬膜下血肿第二次引流后,病理标本诊断为硬脑膜转移。

结论

回顾文献发现,有25例硬脑膜转移合并慢性硬膜下血肿和凝血病的病例。这些病例的特点是,尽管进行了手术引流,但临床结局非常差。这种组合可能是一种独特的疾病实体,认识到这一点对于指导这种罕见疾病的管理很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a51e/3385075/8f0bb594c899/SNI-3-60-g001.jpg

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