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脑膜瘤的异常生长模式。

Unusual growth pattern of a meningioma.

作者信息

Kashimura Hiroshi, Mase Tomohiko, Ogasawara Kuniaki, Kurose Akira

机构信息

Department of Neurosurgery, Iwate Prefectural Chubu Hospital, Kitakami, Iwate, Japan.

出版信息

Surg Neurol Int. 2012;3:63. doi: 10.4103/2152-7806.97007. Epub 2012 Jun 9.

DOI:10.4103/2152-7806.97007
PMID:22754728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3385073/
Abstract

BACKGROUND

Rhabdoid meningioma exhibits high mitotic activity, anaplasia, and increased markers of cell proliferation. Here we describe a rhabdoid meningioma with a pattern of growth extending into the subarachnoid space and filled the cortical sulci.

CASE DESCRIPTION

A 72-year-old woman presented with headache and was admitted to our hospital. Neurologic and physical examinations revealed no abnormalities. Contrast-enhanced axial T1-weighted images showed a well-enhanced, dural-based mass compressing the right temporal and frontal lobes, and extending into the sylvian cistern and filling the cortical sulci. The patient underwent partial resection and the histologic findings demonstrated rhabdoid meningioma.

CONCLUSION

Although this type of tumor is known to be aggressive in its growth, extension into the adjacent cisternal space and the filling of the cortical sulci are rare. The combination of histologic anaplasia with the highest reported proliferation rate, loss of cohesion of neoplastic cells, and the location of the tumor led to the unique growth pattern.

摘要

背景

横纹肌样脑膜瘤表现出高有丝分裂活性、间变以及细胞增殖标志物增加。在此,我们描述一例横纹肌样脑膜瘤,其生长模式延伸至蛛网膜下腔并充满脑沟。

病例描述

一名72岁女性因头痛入院。神经和体格检查未发现异常。增强轴向T1加权图像显示一个强化良好、起源于硬脑膜的肿块,压迫右侧颞叶和额叶,并延伸至外侧裂池并充满脑沟。患者接受了部分切除术,组织学检查结果显示为横纹肌样脑膜瘤。

结论

尽管已知此类肿瘤生长具有侵袭性,但延伸至相邻脑池间隙并充满脑沟的情况罕见。组织学间变与报道的最高增殖率、肿瘤细胞黏附丧失以及肿瘤位置相结合,导致了独特的生长模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/5f956a6a3c6c/SNI-3-63-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/cd890ab5be88/SNI-3-63-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/2f288931bc8e/SNI-3-63-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/5d08519f7a7c/SNI-3-63-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/5f956a6a3c6c/SNI-3-63-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/cd890ab5be88/SNI-3-63-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/2f288931bc8e/SNI-3-63-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/5d08519f7a7c/SNI-3-63-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffec/3385073/5f956a6a3c6c/SNI-3-63-g004.jpg

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本文引用的文献

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Rhabdoid meningioma presenting with subependymal and diffuse meningeal involvement but no mass lesion.横纹肌样脑膜瘤表现为室管膜下和弥漫性脑膜累及,但无肿块病变。
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Long-term experience with World Health Organization grade III (malignant) meningiomas at a single institution.一家机构对世界卫生组织III级(恶性)脑膜瘤的长期经验。
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Rhabdoid and papillary meningioma with leptomeningeal dissemination.
伴有软脑膜播散的横纹肌样和乳头状脑膜瘤。
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Rhabdoid meningioma: clinical features and MR imaging findings in 15 patients.横纹肌样脑膜瘤:15例患者的临床特征及磁共振成像表现
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Unique infiltrating morphology of a meningioma-a case report.
Surg Neurol. 2007 Jul;68(1):99-102; discussion 102. doi: 10.1016/j.surneu.2006.08.086. Epub 2007 Feb 15.
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Intracerebral rhabdoid and papillary meningioma with leptomeningeal spread and rapid clinical progression.伴有软脑膜播散及临床快速进展的脑内横纹肌样和乳头状脑膜瘤
Clin Neuropathol. 2005 Jan-Feb;24(1):1-7.
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Atypical meningioma spreading via the perivascular spaces.非典型脑膜瘤通过血管周围间隙扩散。
AJR Am J Roentgenol. 2002 Mar;178(3):768-9. doi: 10.2214/ajr.178.3.1780768.
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Rhabdoid papillary meningioma.横纹肌样乳头状脑膜瘤。
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"Rhabdoid" meningioma: an aggressive variant.“横纹肌样”脑膜瘤:一种侵袭性变体。
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