Pernot F, Berthelot A, Gairard A
C R Seances Soc Biol Fil. 1978;172(6):1214-9.
High calcium diet induces an hypertension lasting one week in normal rats. In mineralocorticoid treated rats (DOCA + NaCl), the same diet prevents for 10 weeks the increase of arterial blood pressure. Parathyroid activity (estimated by urinary cAMP) is decreased after the high calcium diet. These results confirm the role of the parathyroid glands in mineralocorticoid hypertension in the rat.
高钙饮食可使正常大鼠诱发持续一周的高血压。在给予盐皮质激素处理的大鼠(去氧皮质酮 + 氯化钠)中,相同的饮食可在10周内防止动脉血压升高。高钙饮食后甲状旁腺活性(通过尿环磷酸腺苷估算)降低。这些结果证实了甲状旁腺在大鼠盐皮质激素性高血压中的作用。