Department of Medicine and Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, USA.
J Clin Invest. 2012 Apr;122(4):1191. doi: 10.1172/jci62745.
Clinical vignette: A 59-year-old aeronautical engineer is referred to you for evaluation because of increasing difficulty with job performance over the last several years. Difficulty managing home finances, getting lost driving, and forgetting appointments have become common. Previously outgoing, he is now depressed and irritable. After appropriate neurologic assessment, including brain imaging and metabolic studies, you make the diagnosis of Alzheimer’s dementia and are asked by the patient’s family what treatment is available.
一位 59 岁的航空工程师因过去几年工作表现越来越困难而被转介给您进行评估。他在管理家庭财务、开车迷路和忘记约会方面遇到了困难。他以前性格外向，现在却变得沮丧和易怒。经过适当的神经评估，包括脑部成像和代谢研究，您做出了阿尔茨海默病痴呆的诊断，并被患者家属询问有哪些治疗方法可用。
