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[不动纤毛综合征作为不育的一个原因]

[The immotile cilia syndrome as a cause of sterility].

作者信息

Angulo Cuesta J, Unda Urzaiz M, Larrinaga Izaguirre J R, Zubiaur Libano C, Pérez Fernández A, Flores Corral N

机构信息

Servicio de Urología, Santo Hospital Civil de Bilbao, España.

出版信息

Arch Esp Urol. 1990 Sep;43(7):773-7.

PMID:2275574
Abstract

We investigated the relationship between ciliary dyskinesia--commonly referred to as inmotile cilia syndrome--and sterility. In the past two years, we have accurately diagnosed 6 new cases of a total of 20 suspected as having this condition. To make the diagnosis, complete clinical, radiological, ultrastructural and spermatic work up was performed. All males in the fertile age were found to be sterile with spermatozoides with no motility. Sterility may initially go undetected in these patients due to early intense ORL and respiratory symptoms they present. However, mild forms of this disease entity may be asymptomatic and patients may consult for sterility with a clinical picture of scantily florid chronic bronchitis like that of smokers. Coincidental situs inversus may be useful in making the diagnosis.

摘要

我们研究了纤毛运动障碍(通常称为不动纤毛综合征)与不育之间的关系。在过去两年中,我们在总共20例疑似患有这种疾病的患者中准确诊断出6例新病例。为了做出诊断,进行了全面的临床、放射学、超微结构和精液检查。所有育龄男性均被发现不育,精子无运动能力。由于这些患者早期出现强烈的耳鼻喉科和呼吸道症状,不育症最初可能未被发现。然而,这种疾病实体的轻度形式可能无症状,患者可能因不育前来咨询,临床表现为轻度的慢性支气管炎,类似吸烟者的症状。巧合的内脏反位可能有助于诊断。

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