Vasil'eva S V, Iskandarova K A
N. N. Semenov Institute of Chemical Physics, Academy of Sciences of the USSR, Moscow.
Antibiot Khimioter. 1990 Sep;35(9):30-3.
Comparative experiments on the use of the automated system Bioscreen C (SOS-chromotest program) and the Eims tests for estimating the SOS-inducing and mutagenic activity of chemical compounds belonging to 5 different classes showed that the system was obviously promising and safe in rapid screening of environmental mutagens and carcinogens. Advantages of the system use as well as its prospects, specificity and limitations were revealed.
使用自动系统Bioscreen C(SOS-色测试程序)和Eims测试对属于5个不同类别的化合物的SOS诱导和诱变活性进行比较实验,结果表明该系统在快速筛选环境诱变剂和致癌物方面具有明显的前景和安全性。揭示了该系统使用的优点及其前景、特异性和局限性。