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[神经膜中蛋白质的分布作为神经内膜(间质)液重吸收的一个因素]

[Distribution of proteins in neural membranes as a factor of reabsorption of endoneural (interstitial) fluid].

作者信息

Banin V V, Gasymov E K

出版信息

Arkh Anat Gistol Embriol. 1990 Sep;99(9):47-54.

PMID:2275614
Abstract

An investigation on distribution of horseradish peroxidase (HP) product in the sciatic nerve membranes of albino rats, after HP intravenous injection, has been performed. Getting into the interstitial space of epineurium across the microvessel walls, HP spreads as far as the internal layer of the perineural membrane, forming a distinct gradient of concentration of protein at its border. In 60 min after injection of the tracer the value of the perineural-endoneural gradient for proteins is about 70-80% of the value of the plasma-endoneural gradient. A possible mechanism of the endoneural fluid evacuation, connected with various values of protein concentration in the endoneural space and within the nerve perineural membrane is discussed.

摘要

对白化大鼠静脉注射辣根过氧化物酶(HP)后,对其坐骨神经膜中HP产物的分布进行了研究。HP通过微血管壁进入神经外膜的间隙,扩散至神经束膜的内层,在其边界形成明显的蛋白质浓度梯度。注射示踪剂60分钟后,神经束膜 - 神经内膜间蛋白质梯度值约为血浆 - 神经内膜梯度值的70 - 80%。文中讨论了与神经内膜间隙和神经束膜内蛋白质浓度的不同值相关的神经内膜液排出的可能机制。

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