Kvitnitskiĭ-Ryzhov Iu N, Akimova N V, Beliavskiĭ V G, Matvienko A V, Stepanova L V
Arkh Anat Gistol Embriol. 1990 Sep;99(9):5-19.
Literature data and the authors' results, concerning structural and functional peculiarities of all varieties of the cerebral neuroglia under effect of a cranial-cerebral trauma, neurotropic chemical products and oxygen insufficiency have been considered. Ideas that neuroglial reactions under the conditions mentioned are proved to be constant and in dependence of certain peculiarities of each case are either progressive or regressive. The reaction degree is mainly proportional to the disturbance power. Nevertheless, certain discrepancies (ariactivity including) can be observed; this is also determined by a combination of prerequisites and by a peculiarity of individual reactivity of the CNS. The greatest stability of astroglia has been stated. Possible variations in relation between changes of neurons and gliocytes are mentioned. Suggestions are made that diffuse-focal progressive reactions of macroglia under conditions of neurotoxicoses can be determined not by proliferation of cells, but by their migration.
本文考虑了文献数据以及作者的研究结果,内容涉及颅脑创伤、神经毒性化学产物和缺氧影响下各种脑神经元胶质细胞的结构和功能特性。有观点认为,在上述条件下神经胶质反应被证明是持续存在的,并且根据每个病例的特定特征,反应可能是进行性的或退行性的。反应程度主要与干扰强度成正比。然而,可以观察到某些差异(包括无活性);这也由多种前提条件以及中枢神经系统个体反应性的特殊性所决定。已表明星形胶质细胞具有最大的稳定性。文中提到了神经元和神经胶质细胞变化之间关系的可能差异。有人提出,在神经中毒情况下,大胶质细胞的弥漫性局灶性进行性反应可能不是由细胞增殖决定的,而是由它们的迁移决定的。