Obrist W D, Wilkinson W E
Department of Neurosurgery, University of Pittsburgh, Pennsylvania.
Cerebrovasc Brain Metab Rev. 1990 Winter;2(4):283-327.
Almost 30 years have passed since the first measurement of regional cerebral blood flow in humans by 133Xe clearance. A review of the methodology is presented for the two-dimensional intracarotid method and the related inhalation and IV injection techniques. Emphasis is placed on the mathematical models employed and the blood flow indices derived from them. Similarities and differences between methods are described, and the contribution of each to clinical research is summarized.
自首次通过133Xe清除法测量人体局部脑血流量以来，已过去近30年。本文介绍了二维颈内动脉法及相关吸入法和静脉注射技术的方法学。重点介绍了所采用的数学模型以及从中得出的血流指数。描述了各方法之间的异同，并总结了每种方法对临床研究的贡献。
