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将研究转化为实践(TRIP)——癌症干预对临终关怀中老年人癌症疼痛管理的影响。

The effect of a translating research into practice (TRIP)--cancer intervention on cancer pain management in older adults in hospice.

机构信息

University of Iowa, College of Nursing, Iowa City, IA 52242, USA.

出版信息

Pain Med. 2012 Aug;13(8):1004-17. doi: 10.1111/j.1526-4637.2012.01405.x. Epub 2012 Jul 3.

Abstract

BACKGROUND

Pain is a major concern for individuals with cancer, particularly older adults who make up the largest segment of individuals with cancer and who have some of the most unique pain challenges. One of the priorities of hospice is to provide a pain-free death, and while outcomes are better in hospice, patients still die with poorly controlled pain.

OBJECTIVE

This article reports on the results of a Translating Research into Practice intervention designed to promote the adoption of evidence-based pain practices for older adults with cancer in community-based hospices.

SETTING

This Institutional Human Subjects Review Board-approved study was a cluster randomized controlled trial implemented in 16 Midwestern hospices.

METHODS

Retrospective medical records from newly admitted patients were used to determine the intervention effect. Additionally, survey and focus group data gathered from hospice staff at the completion of the intervention phase were analyzed.

RESULTS

Improvement on the Cancer Pain Practice Index, an overall composite outcome measure of evidence-based practices for the experimental sites, was not significantly greater than control sites. Decrease in patient pain severity from baseline to post-intervention in the experimental group was greater; however, the result was not statistically significant (P = 0.1032).

CONCLUSIONS

Findings indicate a number of factors that may impact implementation of multicomponent interventions, including unique characteristics and culture of the setting, the level of involvement with the change processes, competing priorities and confounding factors, and complexity of the innovation (practice change). Our results suggest that future study is needed on specific factors to target when implementing a community-based hospice intervention, including determining and measuring intervention fidelity prospectively.

摘要

背景

疼痛是癌症患者的主要关注点,尤其是构成癌症患者最大群体的老年人,他们面临着一些最独特的疼痛挑战。临终关怀的首要任务之一是提供无痛死亡,尽管临终关怀的结果更好,但患者仍会在疼痛未得到有效控制的情况下死亡。

目的

本文报告了一项转化研究实践干预措施的结果,该措施旨在促进在社区临终关怀机构中为患有癌症的老年人采用基于证据的疼痛管理实践。

设置

这项经机构人类受试者审查委员会批准的研究是一项在中西部 16 家临终关怀机构中实施的集群随机对照试验。

方法

利用新入院患者的回顾性医疗记录来确定干预效果。此外,还分析了干预阶段结束时从临终关怀工作人员那里收集的调查和焦点小组数据。

结果

癌症疼痛实践指数(一种基于证据的实践的综合衡量指标)在实验组的改善程度并不显著高于对照组。实验组患者的疼痛严重程度从基线到干预后有所下降,但结果无统计学意义(P = 0.1032)。

结论

研究结果表明,有许多因素可能会影响多组分干预措施的实施,包括环境的独特特征和文化、对变革过程的参与程度、竞争优先事项和混杂因素以及创新(实践变革)的复杂性。我们的研究结果表明,未来需要针对实施社区临终关怀干预措施时的具体因素进行研究,包括前瞻性地确定和测量干预的一致性。

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