（短暂性）低血糖在难治性癫痫发作和癫痫中的作用的搭便车指南。

The hitchhiker's guide to the role of (transient) hypoglycemia in refractory seizures and epilepsy.

机构信息

Division of Child Neurology, College of Medicine, University of Oklahoma, Oklahoma City, Oklahoma 73104, USA.

出版信息

Pediatr Neurol. 2012 Aug;47(2):123-4. doi: 10.1016/j.pediatrneurol.2012.04.020.

DOI:10.1016/j.pediatrneurol.2012.04.020

Abstract

Hypoglycemia and hypoglycorrhachia, although they are uncommon causes of refractory seizures and epilepsy, should always be considered because they are potentially treatable conditions. A high index of suspicion and low threshold for testing recurrent blood and at least one cerebrospinal fluid glucose level are required. Jeavons syndrome and other refractory cryptogenic/idiopathic epilepsies may involve symptomatic etiologies, including hyperinsulinism, GLUT1 deficiency, and other metabolic disorders.

摘要

低血糖症和低血糖性脑脊液，虽然它们是难治性癫痫发作和癫痫的罕见原因，但由于它们是潜在可治疗的病症，因此应始终予以考虑。需要高度怀疑和对反复检测血液和至少一次脑脊液葡萄糖水平有较低的门槛。Jeavons 综合征和其他难治性隐源性/特发性癫痫可能涉及症状性病因，包括胰岛素过多症、GLUT1 缺乏症和其他代谢紊乱。