The Center for Hypertension of the People's Hospital of Xinjiang Uygur Autonomous Region, The Center for Diagnosis, Treatment and Research of Hypertension in Xinjiang, Urumqi, China.
BMC Public Health. 2012 Jul 3;12:499. doi: 10.1186/1471-2458-12-499.
BACKGROUND: Chinese Uygur, Kazakh, Mongolian and Han populations represent >90% of the total population of Xinjiang Uygur Autonomous Region, and their genetic backgrounds, customs, culture, and food consumption are different. The effect of ethnic differences on cardiovascular disease risk factors (CRFs; hypertension, obesity, diabetes, dyslipidemia, smoking) can be striking but is rarely studied. We report here the findings of the relationship among these ethnic groups and their CRFs across the four largest ethnic groups of Xinjiang. METHODS: A cross-sectional survey of representative samples was conducted 2002-2008 in Chinese Uygur, Kazakh, Mongolian and Han populations (age >30 years; 4,421 Kazakh, 3884 Han, 3,218 Uygur, and 892 Mongolian individuals) in Xinjiang. RESULTS: A total of 90.4% of Kazakh, 91.9% of Uygur, 90.4% of Mongolian, 85.1% of Han individuals had at least one CRF. Clustering of ≥2 or ≥3 of these risk factors was noted in 65.2% or 32.1% of Kazakh, 64.8% or 33.0% of Uygur, 66.9% or 36.5% of Mongolian as well as 62.0% or 28.3% of Han subjects, respectively. Compared with the Han population, the adjusted odds ratios of ≥1, ≥2, and ≥3 CRFs for Kazakh, Uygur and Mongolian populations were higher (all P<0.001). The age-standardized prevalence of the clustering of ≥1, ≥2, and ≥3 CRFs in Kazakh, Uygur, Mongolian, and Han populations was lower than their counterparts in the NHANES Ш study (USA) but higher than in the InterASIA Study (China). CONCLUSIONS: Ethnic groups living in Xinjiang had striking differences in CRFs. Ethnic-specific strategies should be developed to prevent cardiovascular disease in different ethnic groups.
背景：中国维吾尔族、哈萨克族、蒙古族和汉族人口占新疆维吾尔自治区总人口的 90%以上，他们的遗传背景、习俗、文化和饮食习惯各不相同。民族差异对心血管疾病风险因素（高血压、肥胖、糖尿病、血脂异常、吸烟）的影响可能非常显著，但很少有研究对此进行探讨。我们在此报告了新疆四个主要民族群体之间这些民族群体及其心血管疾病风险因素之间的关系。
方法：2002-2008 年，我们对新疆维吾尔族、哈萨克族、蒙古族和汉族（年龄>30 岁；哈萨克族 4421 人，汉族 3884 人，维吾尔族 3218 人，蒙古族 892 人）进行了具有代表性的横断面调查。
结果：哈萨克族、维吾尔族、蒙古族和汉族人群中，分别有 90.4%、91.9%、90.4%和 85.1%的个体至少有一种心血管疾病风险因素。在哈萨克族、维吾尔族、蒙古族和汉族人群中，分别有 65.2%或 32.1%、64.8%或 33.0%、66.9%或 36.5%和 62.0%或 28.3%的个体存在两种或三种以上心血管疾病风险因素聚集。与汉族人群相比，哈萨克族、维吾尔族和蒙古族人群存在一种或多种心血管疾病风险因素的调整比值比更高（均 P<0.001）。在哈萨克族、维吾尔族、蒙古族和汉族人群中，年龄标准化的心血管疾病风险因素聚集的发生率低于美国 NHANESШ研究（美国）中的相应发生率，但高于亚洲心血管风险研究（中国）中的发生率。
结论：生活在新疆的不同民族之间在心血管疾病风险因素方面存在显著差异。应制定针对不同民族的具体策略来预防心血管疾病。
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