Li Yan, Ma Yi-tong, Yu Zi-xiang, Yang Yi-ning, Li Xiao-mei, Xie Xiang, Liu Fen, Chen You
Department of Coronary Artery Disease No. 1, Heart Center, the First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Jun;33(6):567-71.
To investigate the prevalence rates of triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol in Han, Uygur and Kazakh populations aged over 35 years, in Xinjiang area.
A four-stage randomly selected samples were used to analyze the prevalence rates of lipid levels in different nationalities, ages, sexes based on data from 7 areas in Xinjiang.
(1) TG levels in Xinjiang appeared to be the highest in Han and lowest in Kazakh ethnicities with the means as (1.72 ± 1.45) mmol/L, (1.21 ± 0.93) mmol/L (F = 209.272, P = 0.000) respectively. The highest TC levels were seen in Kazakh with the lowest seen in Uygur, with means as (4.78 ± 1.16) mmol/L, (4.37 ± 1.13) mmol/L (F = 168.796, P = 0.000) respectively. Both HDL-C and LDL-C levels in Kazakh were the highest but remained the same level in Han and Uygur. (2) The value of TG reached the peak at age 45 to 54 in Han and Uygur, and then descending along with ageing. The overall TC level increased along with age but the HDL-C level generally declined with ageing. The LDL-C level showed a waving distribution along with the increase of age. (3) The TG levels were seen higher in men than in women among Han, Uygur and Kazakh but the TC levels of Han and Uygur were lower in men than in women. Both HDL-C and LDL-C levels were also lower in Han and Kazakh males than in females. (4) The prevalence rates of abnormalities were 35.12%, 32.57% and 16.44% on TG; 27.83%, 17.05% and 33.43% on TC; 32.68%, 31.73% and 28.72% HDL-C; 36.95%, 37.02% and 38.00% on LDL-C, respectively.
People with Han and Uygur ethnicities in Xinjiang region had high TG, but low HDL-C distribution of blood lipids while the Kazakh had low TG, high TC, high HDL-C, high LDL-C blood lipids distribution. The distributions of TG levels were different in age, nationality and sex, except the distribution of LDL-C levels. More attention should be paid to the young men of Han and Uygur on prevention of dyslipidemia, in Xinjiang.
调查新疆地区35岁以上汉族、维吾尔族和哈萨克族人群中甘油三酯、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇的患病率。
采用四阶段随机抽样方法,根据新疆7个地区的数据,分析不同民族、年龄、性别的血脂水平患病率。
(1)新疆地区汉族的甘油三酯水平最高,哈萨克族最低,均值分别为(1.72±1.45)mmol/L、(1.21±0.93)mmol/L(F=209.272,P=0.000)。总胆固醇水平最高的是哈萨克族,最低的是维吾尔族,均值分别为(4.78±1.16)mmol/L、(4.37±1.13)mmol/L(F=168.796,P=0.000)。哈萨克族的高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平均最高,而汉族和维吾尔族处于同一水平。(2)汉族和维吾尔族的甘油三酯值在45至54岁达到峰值,然后随年龄增长而下降。总胆固醇水平总体上随年龄增长而升高,但高密度脂蛋白胆固醇水平通常随年龄增长而下降。低密度脂蛋白胆固醇水平随年龄增长呈波浪状分布。(3)汉族、维吾尔族和哈萨克族中男性的甘油三酯水平高于女性,但汉族和维吾尔族男性的总胆固醇水平低于女性。汉族和哈萨克族男性的高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平也低于女性。(4)甘油三酯异常患病率分别为35.12%、32.57%和16.44%;总胆固醇异常患病率分别为27.83%、17.05%和33.43%;高密度脂蛋白胆固醇异常患病率分别为32.68%、31.73%和28.72%;低密度脂蛋白胆固醇异常患病率分别为36.95%、37.02%和38.00%。
新疆地区汉族和维吾尔族人群血脂呈现高甘油三酯、低高密度脂蛋白胆固醇的分布特点,而哈萨克族人群血脂呈现低甘油三酯、高总胆固醇、高高密度脂蛋白胆固醇、高低密度脂蛋白胆固醇的分布特点。除低密度脂蛋白胆固醇水平分布外,甘油三酯水平在年龄、民族和性别上的分布存在差异。在新疆,应更加关注汉族和维吾尔族青年男性血脂异常的预防。