Yoshitoshi E Y, Yoshizawa A, Ogawa E, Kaneshiro M, Takada N, Okamoto S, Fujimoto Y, Sakamoto S, Masuda S, Matsuura M, Nakase H, Chiba T, Tsuruyama T, Haga H, Uemoto S
Department of Hepatobiliary, Pancreas, Transplantation and Pediatric Surgery, Kyoto University Hospital, Graduate School of Medicine, 54 Kawara-cho, Shogoin, Sakyo-ku, Kyoto city, 606-8507, Japan.
Pediatr Surg Int. 2012 Aug;28(8):855-9. doi: 10.1007/s00383-012-3110-x. Epub 2012 Jul 4.
Early diagnosis and treatment of acute cellular rejection (ACR) after intestinal transplantation (ITx) is challenging. We report the outcome of three patients: two presented mild ACR improved with steroids. One presented steroid-resistant severe rejection, improved after rabbit anti-thymocyte globulin (r-ATG), but unfortunately died for encephalitis caused by opportunistic infections.
肠道移植（ITx）后急性细胞排斥反应（ACR）的早期诊断和治疗具有挑战性。我们报告了三名患者的治疗结果：两名患者出现轻度ACR，使用类固醇后病情改善。一名患者出现对类固醇耐药的严重排斥反应，使用兔抗胸腺细胞球蛋白（r-ATG）后病情改善，但不幸的是因机会性感染引起的脑炎死亡。
