Robinson C, Hallsworth A S, Shore R C, Kirkham J
Department of Oral Biology, University of Leeds, UK.
Caries Res. 1990;24(4):226-30. doi: 10.1159/000261272.
It has been proposed that the so-called intact surface zone of carious lesions of enamel could restrict the ingress of mineral ions and hinder remineralisation. The present study was intended to determine the role of organic (proteinaceous) material in restricting the movement of mineral ions into carious lesions in vitro. Natural carious lesion surfaces were divided into two halves. The experimental half was de-proteinised using hypochlorite, the control half remained untreated. The whole tooth was exposed to 45Ca in solution, and 45Ca uptake into experimental and control tissue was measured by image analysis of autoradiographs prepared from lesion sections. The results indicated that uptake was improved by removal of organic material.
有人提出，牙釉质龋损的所谓完整表面层可能会限制矿物质离子的进入并阻碍再矿化。本研究旨在确定有机（蛋白质）物质在体外限制矿物质离子进入龋损中的作用。将天然龋损表面分成两半。实验部分用次氯酸盐脱蛋白，对照部分不做处理。将整颗牙齿置于含有45Ca的溶液中，通过对病变切片制备的放射自显影片进行图像分析，测量实验组织和对照组织对45Ca的摄取。结果表明，去除有机物质后摄取量有所提高。
