Pan Hong-Wei, Iakymenko Stanislav, Xu Jin-Tang, Hou Guang-Hui, Sun Bing-Ji, Zheng A-Ning
Department of Ophthalmology, the First Affiliated Hospital of Jinan University, Guangzhou 510632, Guangdong Province, China.
Int J Ophthalmol. 2012;5(2):167-71. doi: 10.3980/j.issn.2222-3959.2012.02.10. Epub 2012 Apr 18.
To present the results of implantation of Iakymenko keratoprosthesis in five patients with vascularized corneal leukoma caused by severe ocular injury.
Iakymenko keratoprosthesis was implanted into 5 eyes of 5 patients: 4 patients were suffered from chemical burns and 1 patient from explosive injury. The preoperative visual acuity ranged from light perception to hand motion. The implantation surgery was composed of two-stage procedures. The follow-up period was from 9 months to 11 years. The outcome measures were visual acuity, retention, and complications of the keratoprosthesis.
Vision improvements were achieved in most patients. All keratoprosthesis were retained within the follow-up period. Corneal melting occurred in one patient and fibrous closure in another patient, both of which were successfully treated. Retinal detachment occurred in one patient after surgery.
Iakymenko keratoprosthesis seems to be a promising alternative for the patients with severe corneal injury, but further investigation is needed to evaluate the role of Iakymenko keratoprosthesis.
介绍Iakymenko角膜假体植入治疗5例因严重眼外伤导致的血管化角膜白斑患者的结果。
将Iakymenko角膜假体植入5例患者的5只眼中：4例患者为化学伤，1例患者为爆炸伤。术前视力范围从光感至手动。植入手术包括两期操作。随访期为9个月至11年。观察指标为视力、角膜假体的保留情况及并发症。
大多数患者视力得到改善。所有角膜假体在随访期内均得以保留。1例患者发生角膜溶解，另1例患者发生纤维性闭合，二者均得到成功治疗。1例患者术后发生视网膜脱离。
Iakymenko角膜假体似乎是严重角膜损伤患者的一种有前景的替代选择，但需要进一步研究以评估Iakymenko角膜假体的作用。
