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中国西南地区彝族农民和移民的血脂异常患病率及相关因素。

Prevalence of dyslipidemia and associated factors in the Yi farmers and migrants of Southwestern China.

机构信息

Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China.

出版信息

Atherosclerosis. 2012 Aug;223(2):512-8. doi: 10.1016/j.atherosclerosis.2012.06.009. Epub 2012 Jun 18.

Abstract

There are scant data on serum lipid profile in the Yi people in China. The Yi farmers and migrants provide an unusual opportunity to estimate effects of environmental factors on serum lipid levels. We conducted a cross-sectional study in the Yi people to estimate prevalence of dyslipidemia and associated factors. It was found that prevalence of high total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), abnormal ratio of TC/HDL-C and low high-density lipoprotein-cholesterol (HDL-C) were 1.82%, 5.07%, 1.56%, 9.30% and 39.47%, respectively in the Yi farmers. And those in the Yi migrants were 4.81%, 22.21%, 3.24%, 26.56% and 40.53%. Prevalence of dyslipidemia increased with time period in the Yi farmers after their emigrating to urban areas for less than 25 years, except high TC. It was also found that prevalence of dyslipidemia of the Yi migrants increased with time period before their emigration, including hypertriglyceridemia, low HDL-C and high ratio of TC/HDL-C. Their body mass index (BMI), history of type 2 diabetes mellitus (T2DM), gender, ever alcohol drinking and physical activity all were associated with dyslipidemia, but no factors associated with high LDL-C was found. In conclusion, all these results suggest that the Yi migrants have a higher prevalence of dyslipidemia than the Yi farmers do, which possibly can attribute to their urbanized lifestyles.

摘要

在中国,彝族人群的血清脂质谱数据稀缺。彝族农民和移民为评估环境因素对血清脂质水平的影响提供了一个特殊的机会。我们在彝族人群中进行了一项横断面研究,以估计血脂异常的患病率及其相关因素。结果发现,彝族农民中高总胆固醇(TC)、高甘油三酯(TG)、低高密度脂蛋白胆固醇(LDL-C)、TC/高密度脂蛋白胆固醇(HDL-C)比值异常和低 HDL-C 的患病率分别为 1.82%、5.07%、1.56%、9.30%和 39.47%。彝族移民中这些值分别为 4.81%、22.21%、3.24%、26.56%和 40.53%。彝族农民移民到城市居住不足 25 年后,除 TC 外,随着时间的推移,血脂异常的患病率逐渐增加。此外,还发现彝族移民在移民前的时间内,血脂异常的患病率逐渐增加,包括高甘油三酯血症、低 HDL-C 和高 TC/HDL-C。他们的体重指数(BMI)、2 型糖尿病(T2DM)病史、性别、是否饮酒和身体活动都与血脂异常有关,但没有发现与 LDL-C 升高相关的因素。总之,这些结果表明,彝族移民的血脂异常患病率高于彝族农民,这可能与他们的城市化生活方式有关。

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