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中国彝族人群高血压患病率的20年时间趋势:1996 - 2015年三项连续横断面研究

Twenty-year time trends in hypertension prevalence in Yi people of China: three successive cross-sectional studies, 1996-2015.

作者信息

Zhang Jia, Wan Shaoping, Zhang Biao, Dong Fen, Pan Li, Yihuo Wuli, Gong Haiying, Yang Fang, Xu Guodong, Li Zheng, Li Guoju, Li Yanlong, Wang Xiaoyang, Shan Guangliang

机构信息

Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.

Sichuan Provincial Hospital, Chengdu, Sichuan, China.

出版信息

BMJ Open. 2018 Oct 3;8(10):e022714. doi: 10.1136/bmjopen-2018-022714.

Abstract

OBJECTIVE

To explore the trend of hypertension prevalence and related factors in Yi people from 1996 to 2015.

METHODS

Three successive cross-sectional surveys were conducted in Liangshan Yi Autonomous Prefecture in 1996, 2007 and 2015, respectively. A total of 8448 participants aged 20-80 years (5040 Yi farmers, 3408 Yi migrants) were included in final analysis.

RESULTS

Overall, the age-standardised prevalence of hypertension in migrants was significantly higher than in farmers. Furthermore, the age-standardised prevalence rates increased from 10.1% to 15.3% to 19.6% in Yi migrants and from 4.0% to 6.3% to 13.1% in Yi farmers during 1996 to 2007 to 2015. The highest 2015-to-1996 ratio of age-standardised hypertension prevalence was in male farmers (ratio=4.30), whereas despite the highest prevalence of hypertension, the equivalent figure in male migrants was 1.57. The older age, overweight and obesity were persistent risk factors of hypertension in three periods. After adjusted for age and body mass index, the difference of hypertension prevalence between 1996 and 2015 then vanished in male migrants (OR=1.335; 95% CI: 0.884 to 2.015) and female farmers (OR=1.267; 95% CI: 0.590 to 2.719). The disparities of hypertension prevalence between Yi migrants and farmers were not statistically significant in all subgroups when adjusted for age, body mass index and education.

CONCLUSIONS

Over the past two decades, the hypertension prevalence in Yi people has significantly increased. Yi migrants were more likely to be hypertensive than Yi farmers which was predominantly driven by the discrepancy of body mass index between them.

摘要

目的

探讨1996年至2015年彝族人群高血压患病率变化趋势及相关因素。

方法

分别于1996年、2007年和2015年在凉山彝族自治州进行了三次连续的横断面调查。最终分析纳入了8448名年龄在20 - 80岁的参与者(5040名彝族农民,3408名彝族流动人口)。

结果

总体而言,流动人口中高血压的年龄标准化患病率显著高于农民。此外,1996年至2007年再到2015年期间,彝族流动人口的年龄标准化患病率从10.1%升至15.3%再升至19.6%,彝族农民的年龄标准化患病率从4.0%升至6.3%再升至13.1%。2015年与1996年年龄标准化高血压患病率之比最高的是男性农民(比值 = 4.30),而尽管男性流动人口高血压患病率最高,其相应比值为1.57。年龄较大、超重和肥胖在三个时期都是高血压的持续危险因素。在调整年龄和体重指数后,1996年与2015年男性流动人口(比值比 = 1.335;95%置信区间:0.884至2.015)和女性农民(比值比 = 1.267;95%置信区间:0.590至2.719)之间高血压患病率的差异消失。在调整年龄、体重指数和教育程度后,彝族流动人口与农民之间高血压患病率的差异在所有亚组中均无统计学意义。

结论

在过去二十年中,彝族人群高血压患病率显著上升。彝族流动人口比彝族农民更易患高血压,这主要是由他们之间体重指数的差异所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af6d/6194469/2c96a2394a33/bmjopen-2018-022714f01.jpg

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